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  <titleInfo>
    <title>Biology of aging</title>
  </titleInfo>
  <name type="personal">
    <namePart>McDonald, Roger B.</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
  <genre authority="marc">bibliography</genre>
  <originInfo>
    <place>
      <placeTerm type="code" authority="marccountry">flu</placeTerm>
    </place>
    <place>
      <placeTerm type="text">Boca Raton</placeTerm>
    </place>
    <publisher>CRC Press/Taylor &amp; Francis</publisher>
    <dateIssued>c2019</dateIssued>
    <dateIssued encoding="marc">2019</dateIssued>
    <edition>2nd ed.</edition>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
  <physicalDescription>
    <form authority="marcform">print</form>
    <extent>xxii, 432 p. : ill. (chiefly col.) </extent>
  </physicalDescription>
  <abstract>Biology of Aging presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanism underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material.</abstract>
  <tableOfContents>Basic concepts in the biology of aging -- Measuring biological aging -- Evolutionary theories of longevity and aging -- Cellular aging -- Genetics of longevity -- Plant senescence -- Human longevity and life span -- Common functional loss associated with aging -- Common time-dependent disease in humans -- Modulating human aging and longevity -- The implications of an extended healthspan -- Appendix: US life table calculations.</tableOfContents>
  <note type="statement of responsibility">Roger B. McDonald.</note>
  <note>Includes bibliographical references and index.</note>
  <subject>
    <topic>Aging</topic>
    <topic>Physiology</topic>
  </subject>
  <subject>
    <topic>Cellular senescence</topic>
    <topic>Physiology</topic>
  </subject>
  <subject>
    <topic>Longevity</topic>
    <topic>Physiology</topic>
  </subject>
  <classification authority="nlm">WT104 .M336 2019</classification>
  <identifier type="isbn">9780815345671</identifier>
  <identifier type="isbn">0815345674</identifier>
  <recordInfo>
    <recordCreationDate encoding="marc">210326</recordCreationDate>
    <recordIdentifier source="OCoLC">on1056201427</recordIdentifier>
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